In the natal chart if your ascendant is Mithuna (Gemini)then the lord of your Lagna and fourth house is Mercury. Mercury for you is Yogkaraka or auspicious as he is the Lord of Kendra 4th and Trikona 1st . Saturn is the Lord of your eighth house & ninth house, one being Ashtama Bhava or inauspicious bhava and the other being ninth one of the trikona(Triangular) here Saturn stands as mildly auspicious or neutral. Venus is the Lord of your fifth House and twelfth house respectively. One house being the Trikona and the other being Trika or inauspicious and owing to the friendship to the Lagna Lord Mercury is auspicious. The inauspiciousness due to the Twelfth house is taken as negligible. However during its Mahadasha or the period of its reigning Venus due to Lord of twelfth house makes the native to spend lavishly ofcourse for good cause. The second house owner Moon being friend to Mercury gives neutral results. The Lord of third house Sun is also neutral in this case as he is neutral to Surya or Sun. The Lord of eighth and eleventh house Mars is highly malefic as he is a great enemy to the Lord of Lagna Mercury. The Lord of seventh house and 10th house Jupiter in this case is also inimical as he is great enemy to the Lord of Lagna Mercury. . Rahu in astrology is considered as Saturn and Ketu as mars. Hence Rahu is auspicious and Ketu inauspicious.
KARKATAKA LAGNA OR CANCER
Moon as the Lord of Cancer (Karkataka)
In the natal chart if your ascendant is Cancer (Karkataka) then the lord of your Lagna is Moon. Jupiter is the Lord of your ninth house and Lord of sixth House. Being the Lord of sixth house and ninth house and the being the best friend of Lagna Lord Chandra (Moon) Jupiter is considered as benefic for this Lagna. The fifth house and tenth house Lord is Mars and being the best friend of Chandra (Moon) He is considered as Yogkaraka for this Ascendants. The second house Lord is Surya who is considered as the friend is also benefic to this Lagna. The 3rd house and 12th house Lord Mercury who considers himself as an enemy to Moon gives very bad results to this Lagna. Venus too is taken as an enemy and being the Lord of 4th and 11th . Though 4th house is neutral but 11th house is a bit malefic hence Venus is malefic for the jatakas with this Lagna. Saturn is the lord of 7th and 8th house, though 7th house is neutral but 8th is very bad according to Vedic astrology. Saturn is also very inimical to Chandra or Moon hence Saturn for this jatakas is very bad. Rahu and Ketu both are enemies to Chandra the Lagna Lord hence both gives bad results.